Project Description

In 2016 Dr. Mario Thevis was awarded a PCC Micro-Grant for a pilot study entitled “Exhaled Breath as a Potential Alternative Matrix in Doping Controls.”

The research will examine the ability of a non-invasive breath testing device to detect agents commonly abused in sport. The technology, which has already been proven to detect drugs of abuse such as cocaine, was designed by SensAbues in Sweden. The PCC is excited to collaborate with an innovative organization to determine the applicability of the technology for anti-doping purposes.

Dr. Thevis’s micro-grant is designed to gather preliminary data regarding the breath testing device’s ability to effectively and efficiently detect analytes such as hGH and IGF-1. Additional robust studies will follow if the pilot goes well.

How it works: 

The technology would collect ‘bioaerosol particles’, which are liquid microparticles created by the closing and opening of bronchioles during normal breathing processes. The particles form a ‘bioaserol’ which is exhaled alongside the breath, and can be filtered by the innovative technology developed at the Karolinska Institute. Collected particles can be used to detect drugs of abuse using analysis techniques with high sensitivity, for example liquid chromatography – mass spectrometry.

The technology has the potential to replace or supplement more intrusive collection methods such as urine and blood samples, providing a less expensive, on-site collection option for anti-doping administrators, and a more pleasant sample collection experience for athletes.

For more information about the technology’s current applications, visit Manual Sensabues DrugTrap.